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Detection of clonality in follicular lymphoma using formalin-fixed, paraffin-embedded tissue samples and BIOMED-2 immunoglobulin primers

✍ Scribed by Berget, E.; Helgeland, L.; Molven, A.; Vintermyr, O. K.


Book ID
125855392
Publisher
BMJ Publishing Group
Year
2010
Tongue
English
Weight
194 KB
Volume
64
Category
Article
ISSN
0021-9746

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The most common genetic aberration in follicular lymphoma (FL) is the t(14;18)(q32;q21) translocation that juxtaposes the antiapoptotic BCL2 gene with the promoter of the immunoglobulin heavy chain (IgH) gene. Our aim was to test the usefulness of two different techniques, fluorescence in situ hybri