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Detection of chromosome 11 alterations in blood and bone marrow by interphase cytogenetics in mantle cell lymphoma

✍ Scribed by Emanuele Zucca; Gianni Soldati; Brigitte Schlegelberger; Mark J. Booth; Klaus Weber-Matthiesen; Franco Cavalli; Finbarr E. Cotter

Book ID
114714452
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
344 KB
Volume
89
Category
Article
ISSN
0007-1048

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## BACKGROUND. The cytomorphologic diagnosis of mantle cell lymphoma (MCL) can be difficult and requires ancillary studies for accurate subclassification. More than 95% of MCLs are known to carry the t(11;14) chromosomal translocation. However, traditional cytogenetic studies on cytologic material