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Detection of chromosomal abnormalities in uterine leiomyoma using conventional cytogenetic method and interphase fluorescence in situ hybridization

✍ Scribed by Satoshi Hayashi; Norio Miharu; Etsuji Okamoto; Osamu Samura; Tetsuaki Hara; Koso Ohama


Book ID
113253739
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
621 KB
Volume
89
Category
Article
ISSN
0165-4608

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✍ Jo-Ann K. Brock; Wei-Hua Liu; S. Terrell Smith; S. Robert Young πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 801 KB

Fluorescence in situ hybridization was used in interphase cells of 30 ovarian carcinomas to detect numerical changes in copy number of I 3 different centromeres (I, 2.3,4,6.7,8, 10. I I, I 2, 17, 18, and X). Thirty-seven percent of samples ( I I /30) were near diploid and demonstrated only minor cha