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Detection of cadmium ion using the fluorescence probe Indo-1

✍ Scribed by T. Vo-Dinh; P. Viallet; L. Ramirez; A. Pal; J. Vigo

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 526 KB
Volume: 295
Category: Article
ISSN: 0003-2670
DOI: 10.1016/0003-2670(94)80335-8

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✦ Synopsis

Fluorescence probes for biosensors used for the determination of intracellular concentration of metal ions have been synthesized in order to bind selectively with a specific cation. Since certain ions exhibit similar chemical properties, binding selectivity with the probes is difficult. In this paper we describe for the first time the interaction between Indo-1, a fluorescence probe representative of a family of "specific chelating compounds" (mainly used for calcium) with the cadmium ion. The fluorescence properties of the cadmium complex are described and a method is proposed to determine the concentrations of both calcium and cadmium ions in aqueous solutions.

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