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Detection of bulky DNA lesions in the liver of patients with Wilson's disease and primary haemochromatosis

✍ Scribed by Paul L. Carmichael; Alan Hewer; Martin R. Osborne; Alastair J. Strain; David H. Phillips


Book ID
113194463
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
922 KB
Volume
326
Category
Article
ISSN
0027-5107

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## Abstract Bulky DNA damage is corrected by the nucleotide excision repair (NER) pathway. Although the core biochemical mechanism of NER is understood, details including lesion recognition and repair in the context of chromatin remain to be elucidated. As more data become available, the complexity