## Abstract Blood oxygenation level dependent (BOLD) functional MRI (fMRI) is an important method for functional neuroimaging that is sensitive to changes in blood oxygenation related to brain activation. While BOLD imaging has good spatial coverage and resolution relative to other neuroimaging met
Detection of brain activation using oxygenation sensitive functional spectroscopy
✍ Scribed by J. Hennig; Th. Emst; O. Speck; G. Deuschl; E. Feifel
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 628 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A nonwater‐suppressed localized spectroscopy experiment using the PRESS‐sequence has been used to study the signal changes of the water resonance during cortical activation. Significant effects with an effect‐to‐noise ratio up to 50:1 for a single shot experiment have been observed upon photic stimulation. The exceedingly high signal‐to‐noise ratio of the experiment was used to demonstrate signal changes as low as 0.1% after electrical stimulation of the median nerve.
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