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Detection of bound and free IGF-1 and IGF-2 in human plasma via biomolecular interaction analysis mass spectrometry

✍ Scribed by Dobrin Nedelkov; Randall W. Nelson; Urban A. Kiernan; Eric E. Niederkofler; Kemmons A. Tubbs

Book ID
117105093
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
147 KB
Volume
536
Category
Article
ISSN
0014-5793

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## Abstract Overexpression of insulin‐like growth factor‐1 (IGF‐1) has been associated with a number of human tumors, including breast, colon, lung, and prostate cancers. In previous studies, we found that mice overexpressing human IGF‐1 in the basal layer of the epidermis (BK5.IGF‐1 mice) develope