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Detection of BK virus antibodies measured by enzyme-linked immunosorbent assay (ELISA) and two haemagglutination inhibition methods: A comparative study

✍ Scribed by Trond Flaegstad; Terje Traavik


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
316 KB
Volume
16
Category
Article
ISSN
0146-6615

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✦ Synopsis


Abstract

We developed a solid phase enzyme‐linked immunosorbent assay (ELISA) for detecting IgG antibodies to BK virus (BKV). This test was compared to two haemagglutination inhibition methods, one using receptor‐destroying enzyme and the other NaIO~4~ to remove nonspecific inhibitors. The results show that this single dilution ELISA is a sensitive and specific test. The inherent advantages of this method make it an attractive alternative for the seroepidemiology of BKV.