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Detection of anti-Ro(SSA) antibodies by gel double diffusion and a ‘sandwich’ ELISA in systemic and subacute cutaneous lupus erythematosus and Sjögren's syndrome

✍ Scribed by Provost, Thomas T.; Levin, L.Stefan; Watson, Rosemarie M.; Mayo, Marvin; Ratrie, Harry


Book ID
121950278
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
718 KB
Volume
4
Category
Article
ISSN
0896-8411

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Patients with subacute cutaneous lupus erythematosus (SCLE) have circulating antibodies to Ro/SSA directed to two antigenically distinct ribonucleoproteins of 60 kDa and 52 kDa. Three laboratory tests may be used to detect anti-Ro/SSA antibodies: counterimmunoelectrophoresis (CIE), enzyme-linked imm