A microtiter plate was coated with cell nuclei from HEp-2 cells, and the stabilized nuclei were fixed with acetone for an enzymelinked immunosorbent assay (ELISA). Autoantibodies against nuclear antigens were detected from the sera of patients with various systemic rheumatic disease but not from hea
Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus
β Scribed by Yongchu Huang; Jing Li; Xuejun Zhu
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 311 KB
- Volume
- 301
- Category
- Article
- ISSN
- 0340-3696
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## Abstract ## Objective SjΓΆgren's syndrome (SS) is an autoimmune disease affecting primarily the salivary and lacrimal glands, leading to dry mouth and dry eyes. Recent studies have suggested that autoantibodies reactive with the type 3 muscarinic acetylcholine receptors (M3Rs) expressed on saliv