Detection of aneuploidy in human oocytes and corresponding first polar bodies by fluorescent in situ hybridization
β Scribed by Andrei Dyban; Michael Freidine; Elena Severova; Jeanine Cieslak; Victor Ivakhnenko; Yury Verlinsky
- Book ID
- 105450534
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 744 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1573-7330
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A multicolor fluorescence in situ hybridization (FISH) method was developed to detect aneuploidy and diploidy in epididymal sperm of rats using DNA probes specific for chromosomes 4 and Y. Fourteen healthy young-adult rats from three strains were evaluated: inbred Fisher 344/N/ehs, outbred Sprague-D
## Abstract A multicolor procedure employing fluorescence in situ hybridization is described for detecting chromosomal domains and germinal aneuploidy in lateβstep spermatids in mice using DNA probes specific for repetitive sequences near the centromeres of chromosomes 8 and X. These probes were ni
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