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Detection of Amyloid Signature in the Lens and Its Correlation in the Brain to Aid in the Diagnosis of Alzheimer's Disease

✍ Scribed by Kerbage, C.; Sadowsky, C. H.; Tariot, P. N.; Agronin, M.; Alva, G.; Turner, F. D.; Nilan, D.; Cameron, A.; Cagle, G. D.; Hartung, P. D.


Book ID
124167190
Publisher
SAGE Publications
Year
2014
Tongue
English
Weight
346 KB
Volume
30
Category
Article
ISSN
1533-3175

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## Abstract Proteolytic processing of the amyloid precursor protein by Ξ² ‐and γ‐secretases results in the production of Alzheimer's disease (AD) AΞ² amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve