Detection of alcohol consumption during pregnancy—Current and future biomarkers
✍ Scribed by Yoav Littner; Cynthia F. Bearer
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 198 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0149-7634
No coin nor oath required. For personal study only.
✦ Synopsis
Alcohol, one of the most frequently reported addictions, is a significant public health problem in the USA. Early identification is important and would aid in intervention for the pregnant woman who continues to drink and for the affected infant. To date, there isn't a definitive test which identifies either alcohol abuse during pregnancy or newborns exposed to alcohol prenatally. The existing biomarkers can detect varying degrees of alcohol exposure but further research is needed to improve sensitivity/specificity and to validate these markers.
📜 SIMILAR VOLUMES
## Abstract A new validated method for the quantitation of the abnormal phospholipid phosphatidylethanol (PEth)—a biomarker for ethanol uptake—has been developed by LC‐ESI‐MS/MS following miniaturised organic solvent extraction and reversed phase chromatography with phosphatidylbutanol (PBut) as in
## Abstract ## BACKGROUND The classic clinical criteria for the diagnosis of fetal alcohol syndrome (FAS) include a “characteristic” facial appearance, pre‐ and postnatal growth deficiency, microcephaly, mental retardation, and occasional major malformations. However, diagnostic constraints, espec