Detection of aberrant methylation of 10 genes in genomic DNA of lung tumors
โ Scribed by Sheikhnejad, R.; Zohri, M.; Shadmehr, M. B.; Rahmani-Khalili, M.; Doozande, N.; Farsad, Z.; Sheikhzade, K.
- Book ID
- 121412278
- Publisher
- Oxford University Press
- Year
- 2013
- Tongue
- English
- Weight
- 51 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0923-7534
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Our previous studies revealed a variety of genetic changes in lung cancers from chromate-exposed workers (chromate lung cancer). In the present study, we examined epigenetic changes in chromate lung cancers. Nestedmethylation-specific PCR was employed in studying the methylation of CpG islands in th
## Abstract Investigating aberrant DNA methylation in the cancer genome may identify genes that play an important role in tumor progression. In this study, we combined differential methylation hybridization and a CpG microarray platform to characterize methylation profiles and identify novel candid