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Detection of 3-deoxyglucosone-derived AGE structures in vitro

โœ Scribed by Tadashi Jono; Ryoji Nagai; Kiminori Miyazaki; Naila Ahmed; Paul J Thornalley; Toshinori Kitamura; Seikoh Horiuchi


Book ID
117550741
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
56 KB
Volume
1245
Category
Article
ISSN
0531-5131

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3-Deoxyglucosone and AGEs in uremic comp
โœ Niwa, Toshimitsu; Tsukudhi, Saori ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 881 KB

3-deoxyglucosone (3-DG) is accumulated not only in uremic serum but also in uremic erythrocytes. 3-DG rapidly reacts with protein amino groups to form advanced glycation end products (AGEs) such as imidazolone, pyrraline, and N(epsilon)-(carboxymethyl)lysine, among which imidazolone is the AGE that