Detection limit of architect hepatitis C core antigen assay in correlation with HCV RNA, and renewed confirmation algorithm for reactive anti-HCV samples
β Scribed by Ottiger, Cornelia; Gygli, Nicole; Huber, Andreas R.
- Book ID
- 121194778
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 506 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1386-6532
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## Abstract A new, sensitive enzyme immunoassay has been developed for detecting and quantifying total hepatitis C virus (HCV) core antigen in antiβHCV positive or negative sera (β__trak__β__C__β’β, Ortho Clinical Diagnostics, Raritan, NJ). The purpose of this study was to evaluate the performance o
Extensive serological testing and HCV RNA determination by RT-PCR was performed in serum, PBMCs, and liver tissue i n thirteen anti-HCV reactive patients with persistently normal liver tests. Absolute concordance in the status of HCV RNA between serum, PBMCs, and liver was noted. Five patients were