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Detection by polymerase chain reaction of herpes simplex virus type 1 (HSV1) DNA in brain of aged normals and Alzheimer's disease (AD) patients


Book ID
122774386
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
182 KB
Volume
13
Category
Article
ISSN
0197-4580

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Detection of herpes simplex virus type 1
โœ Hisako Motani; Koichi Sakurada; Hiroshi Ikegaya; Tomoko Akutsu; Mutsumi Hayakawa ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 108 KB

Herpes simplex virus type 1 (HSV-1) DNA was extracted from human trigeminal ganglia of 121 cadavers aged between 3 months and 94 years, and its PCR amplification was performed for the RL2 HSV-1 sequence using two pairs of primers. The HSV-1 DNA was detected in 74 of 121 patients (61%); 70/74 bilater