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Detection and Structural Characterization of Glutathione-Trapped Reactive Metabolites Using Liquid Chromatography−High-Resolution Mass Spectrometry and Mass Defect Filtering

✍ Scribed by Ma, Li; Zhang, Haiying; Humphreys, W. Griffith; Zhu, Mingshe


Book ID
115466400
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
305 KB
Volume
79
Category
Article
ISSN
0003-2700

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## Abstract The present study describes a new analytical approach for the detection and characterization of chemically reactive metabolites using glutathione ethyl ester (GSH‐EE) as the trapping agent in combination with hybrid triple quadrupole linear ion trap mass spectrometry. Polarity switching