Persistent infection of the uterine cervix with high-risk human papillomaviruses (HPV) is causally associated with cancer of the cervix. A few studies have reported the presence of HPV DNA in the blood of women with cervical neoplasia. The aim of this study was to determine if HPV DNA could be detec
Detection and quantitation of HPV 16 and 18 in plasma of Indian women with cervical cancer
β Scribed by Manu Gnanamony; Abraham Peedicayil; John Subhashini; Thomas Samuel Ram; Anuradha Rajasekar; Patti Gravitt; Priya Abraham
- Book ID
- 113962313
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 145 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0090-8258
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## Abstract Human papilloma virus is a causative factor in the etiology of cervical cancer with HPV16 being the most prevalent genotype associated with it. Intratype variations in oncogenic E6/E7 and capsid L1 proteins of HPV 16 besides being of phylogenetic importance, are associated with risk of
## Abstract The clinical utility of HPV 16 and 18 viral loads remains debated. The aim of this study was to assess the clinical significance of HPV 16 and 18 viral load and to determine a cutβoff for optimal prediction of grade 2 or higher cervical intraepithelial neoplasia among patients referred