Detection and quantification of CBFB/MYH
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Jürgen Krauter; Wolf Hoellge; Mike Peter Wattjes; Stefan Nagel; Olaf Heidenreich
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Article
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2001
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John Wiley and Sons
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English
⚖ 156 KB
We used a newly established real-time RT-PCR assay for the quantification of the leukemia-specific CBFB/MYH11 transcripts in inv( 16)-positive acute myeloblastic leukemia. CBFB/MYH11 could be quantified over a five log range, with a detection limit of 10 molecules of a CBFB/MYH11 plasmid and a 1:10