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Detecting retinoic acid-induced biochemical alterations in squamous cell carcinoma using intrinsic fluorescence spectroscopys

โœ Scribed by Michael B. Silberberg; Howard E. Savage; Peter G. Sacks; Stimson P. Schantz; G. C. Tang; Robert R. Alfano


Book ID
115044269
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
456 KB
Volume
104
Category
Article
ISSN
0023-852X

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## Abstract ## Background and Objectives Studies of 5โ€aminolevulinic acidโ€induced protoporphyrin IX fluorescence have shown a sensitivity of 95โ€“100% for oral cancer diagnosis, but the specificity is only about 50โ€“60%. Here, we explore the applicability of quantifying PPIX fluorescence images to im