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Detecting native-like properties in combinatorial libraries of de novo proteins

✍ Scribed by Sushmita Roy; Kimberly J. Helmer; Michael H. Hecht


Book ID
114382612
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
62 KB
Volume
2
Category
Article
ISSN
1359-0278

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An investigation into the native-like pr
✍ Heidi E. K. Huttunen-Hennelly; John C. Sherman πŸ“‚ Article πŸ“… 2007 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 354 KB πŸ‘ 2 views

## Abstract We investigated the hydrophobic packing of two previously designed caviteins, LG2 and LG3, which differ by one Gly in the linker regions between the peptide sequence and the cavitand scaffold. We sought to diminish the putative native‐like properties of LG2 and LG3, and see if we could