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Detailed sequence and haplotype analysis of the beta-2 adrenergic receptor gene in Caucasians and African Americans

โœ Scribed by Meyers, D.A.; Hawkins, G.A.; Tantisira, K.; Ampleford, E.J.; Hernandez, M.; Richter, B.; Peters, S.P.; Liggett, S.B.; Weiss, S.T.; Bleecker, E.R.


Book ID
119275541
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
44 KB
Volume
115
Category
Article
ISSN
1097-6825

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Background The beta-3-adrenergic receptor (b3AR) stimulates lipolysis and thermogenesis in adipocytes. The Trp64Arg b3AR variant is associated in some, but not all, studies with an earlier onset of Type 2 diabetes mellitus and features of the insulin resistance syndrome. Functional studies as to the