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Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules

✍ Scribed by John Sidney; Shinichi Asabe; Bjoern Peters; Kelly-Anne Purton; Josan Chung; Timothy J. Pencille; Robert Purcell; Christopher M. Walker; Francis V. Chisari; Alessandro Sette


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
378 KB
Volume
58
Category
Article
ISSN
0093-7711

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he allele-specific peptidebinding motifs of major histocompatibility complex (MHC) proteins, originally discovered by pool sequencing of MHC class I-bound peptides 1 , provide a biochemical basis for the phenomenon of MHC restriction of T-cell responses. However, the analysis of class II peptide mot