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Detachment and cytolysis of human endothelial cells by proteinase 3

✍ Scribed by Bart E. P. B. Ballieux; Pieter S. Hiemstra; Ngaisah Klar-Mohamad; E. Christiaan Hagen; Leendert A. van Es; Fokko J. van der Woude; Mohamed R. Daha


Book ID
102826791
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
621 KB
Volume
24
Category
Article
ISSN
0014-2980

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## Objective: To assess the ability of anti-proteinase 3 (anti-pr3) classic antineutrophil cytoplasmic antibodies (canca) to stimulate endothelial expression of tissue factor (tf), which is the main initiator of the coagulation cascade that can lead to endothelial injury and thrombosis in patients