Desymmetrization of Meso 1,3- and 1,4-Diols with a Dinuclear Zinc Asymmetric Catalyst
β Scribed by Trost, Barry M.; Mino, Takashi
- Book ID
- 126193959
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 59 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
A novel C~-symmetric bis-sulfoxide 1 was synthesized as a chiral auxiliary for asymmetric desymmetrization of meso-1,2-diols. cis-Cyclohexane-1,2-dioi and cis-cyclopentane-1,2-diol were desymmetrized via acetalization with I followed by basepromoted acetal cleavage with high diastereoselectivity (>9
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