✦ LIBER ✦
Desulphurative approaches to penem antibiotics. IV. Bromination of 3-methyl-2-thiacephems, a novel entry in the synthesis of potent antimicrobial agents
✍ Scribed by Ettore Perrone; Marco Alpegiani; Angelo Bedeschi; Franco Giudici; Maurizio Foglio; Giovanni Franceschi
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 275 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The 3-methyl group in 2-thiacephem-4-carboxylates can be brominated in good yield, thus providing access to a series of highly active penem antibiotics.
References and Notes