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Desmin filaments and cardiac disease: Establishing causality

✍ Scribed by Xuejun Wang; Hanna Osinska; A.Martin Gerdes; Jeffrey Robbins


Book ID
119764019
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
268 KB
Volume
8
Category
Article
ISSN
1532-8414

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Desmin filaments are muscle-specific intermediate filaments located at the periphery of the Z-discs, and they have been postulated to play a critical role in the lateral registration of myofibrils. Previous studies suggest that intermediate filaments may be involved in titin assembly during the earl