Designing Nonviral Vectors for Efficient Gene Transfer and Long-Term Gene Expression
β Scribed by JACKSON, D; JURANEK, S; LIPPS, H
- Book ID
- 111647086
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 492 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1525-0016
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Vectors based on components of Epstein-Barr virus (EBV) have found increasingly wide applications in biotechnology. Three areas of recent advancement comprise the use of EBV vectors to improve the convenience of gene expression systems, the development of EBV vectors for gene transfer in gene therap
## Abstract ## Background Phage ΟC31 integrase has emerged as a potent tool for achieving longβterm gene expression in different tissues. The present study investigated the activity of ΟC31 integrase in murine lungs. ## Methods Transfections in murine alveolar epithelial (MLE12) cells were perfo