๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Designing Libraries with CNS Activity

โœ Scribed by Ajay, ; Bemis, Guy W.; Murcko, Mark A.


Book ID
121698038
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
151 KB
Volume
42
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Rational design of a targeted combinator
โœ Weifan Zheng; Sung Jin Cho; Alexander Tropsha ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 241 KB ๐Ÿ‘ 2 views

We describe a new computational approach, called Focus-2D, to the rational design of targeted combinatorial chemical libraries. This approach is based on the hypothesis that structurally similar compounds display similar biological activity profiles. Building blocks that are used in a combinatorial