Designing for topical delivery: Prodrugs
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Kenneth B. Sloan; Scott Wasdo
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Article
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2003
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John Wiley and Sons
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English
โ 313 KB
It has been shown for homologous series of prodrugs that those members who were the more water soluble ones gave the greatest enhancement in topical delivery of the parent drug and not the more lipophilic ones. However, until recently models for topical delivery and equations to predict topical deli