Designing Fluorescent Sensors of Heparin

✍ Scribed by Jimena C. Sauceda; Rebecca M. Duke; Mark Nitz

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 154 KB
• Volume: 8
• Category: Article
• ISSN: 1439-4227
• DOI: 10.1002/cbic.200600361

✦ Synopsis

Supporting information for this article is available on the WWW under http://www.chembiochem.org or from the author: experimental procedures for the peptide synthesis and fluorescence measurements as well as the 1 H NMR spectra of compounds 1 and 4 are available.

Scheme 1. Changes in the counter ions around the quinolinium sensor lead to a dramatic increase in fluorescence intensity upon heparin association.