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Designing DNA-binding proteins on the surface of filamentous phage

✍ Scribed by Yen Choo; Aaron Klug

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 677 KB
Volume: 6
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(95)80073-5

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✦ Synopsis

The strategy of molecular evolution by phage display recently has been applied to the study of interactions between protein and DNA. This technology will imminently enable DNA-binding proteins to be made to measure. In the first instance, this will greatly advance our understanding of protein-DNA interactions, but in the long term, it is expected to yield powerful tools for use in medicine and research.

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