𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Designing Antibacterial Compounds Through a Topological Substructural Approach.

✍ Scribed by Enrique Molina; Humberto Gonzalez Diaz; Maykel Perez Gonzalez; Elismary Rodriguez; Eugenio Uriarte


Publisher
John Wiley and Sons
Year
2004
Weight
50 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Designing novel antitrypanosomal agents
✍ Alejandro Speck Planche; Marcus Tulius Scotti; Vicente de Paulo Emerenciano; Amé 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 534 KB

## Abstract Chagas disease is nowadays the most serious parasitic health problem. This disease is caused by __Trypanosoma cruzi__. The great number of deaths and the insufficient effectiveness of drugs against this parasite have alarmed the scientific community worldwide. In an attempt to overcome

A topological substructural approach for
✍ Miguel Angel Cabrera; Isabel González; Carlos Fernández; Carmen Navarro; Marival 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

A topological substructural molecular design approach (TOPS-MODE) has been used to predict whether a given compound is a P-glycoprotein (P-gp) substrate or not. A linear discriminant model was developed to classify a data set of 163 compounds as substrates or nonsubstrates (91 substrates and 72 nons