Self-designing clinical trials
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Lloyd D. Fisher
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Article
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1998
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John Wiley and Sons
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English
β 115 KB
π 2 views
I present a method of sequential analysis for randomized clinical trials that allows use of all prior data in a trial to determine the use and weighting of subsequent observations. One continues to assign subjects until one has 'used up' all the variance of the test statistic. There are many strateg