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Designing a simple multiplex ligation-dependent probe amplification (MLPA) assay for rapid detection of copy number variants in the genome

✍ Scribed by Yiping Shen; Bai-Lin Wu

Book ID
118651217
Publisher
Elsevier
Year
2009
Tongue
Chinese
Weight
627 KB
Volume
36
Category
Article
ISSN
1673-8527

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## Abstract Recent genomic studies have shown that copy number abnormalities (CNA) of genes involved in lymphoid differentiation and cell cycle control are common in B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). We have evaluated Multiplex Ligation‐dependent Probe Amplification (MLPA) on