Design, synthesis, structure and binding properties of PDZ binding, cyclic β-finger peptides
✍ Scribed by Sabine Seedorff; Christian Appelt; Michael Beyermann; Peter Schmieder
- Book ID
- 116300196
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 552 KB
- Volume
- 395
- Category
- Article
- ISSN
- 0006-291X
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📜 SIMILAR VOLUMES
Macrocyclic receptor 9, has been prepared in homochiral form. The receptor shows selectivity for cextain dipeptides, and most notably a strong prefea, ence for N-Clyz-l~-alanyl amino acids ovetN-Cbz-~alanyl lactic acids.
Macrocyclic receptor 1 has been synthesised, as a racemate and as a single enantiomer, utilising a Stille coupling for the formation of the biphenyl portion and a macrolactamisation as the final step. The binding properties for the racemic and the homochiral macrocycle with amino acid and dipeptide