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Design, synthesis characterization and in vitro biological activity of a series of 3-aryl-6-(bromoarylmethyl)-7H-thiazolo[3,2-b]-1, 2, 4-triazin-7-one derivatives as the novel acetylcholinesterase inhibitors

✍ Scribed by He Nan Xu; Zhe Jin; Si Jie Liu; Hong Min Liu; Shuo Li; Huang Quan Lin; David Chicheong Wan; Chun Hu


Book ID
116350345
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
292 KB
Volume
23
Category
Article
ISSN
1001-8417

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## Abstract magnified image A series of novel 6‐aryl‐3‐(1,2,3,4‐tetrahydroxybutanol‐1‐yl)‐7__H__‐1,2,4‐triazolo[3,4‐__b__][1,3,4]thiadiazines were easily synthesized in high yields by means of the reactions of 4‐amino‐5‐(1,2,3,4‐tetrahydroxybutyl)‐2,4‐dihydro‐3__H__‐1,2,4‐triazole‐3‐thione (**1**)