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Design, synthesis, and urease inhibition studies of a series of 4-amino-5-aryl-3H-1,2,4-triazole-3-thiones

โœ Scribed by Mahmood-ul-Hassan Khan; Shahid Hameed; Khawaja A. Yasin; Tashfeen Akhtar; Khalid M. Khan


Book ID
106214440
Publisher
Springer Vienna
Year
2010
Tongue
English
Weight
254 KB
Volume
141
Category
Article
ISSN
0026-9247

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โœ Vinay A. Sunagar; Prashant R. Latthe; Bharati V. Badami ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 568 KB

The Schiff bases 3a-h obtained from 4-amino-1,2,4-triazol-3-ones 1a-h when subjected to Japp-Klingemann reaction yielded the corresponding 3-{2-[(2-aryl-5-methyl-3H-[1,2,4]-triazol-3-one-4-yl)]-iminophenyl}-pentane-2,4-diones 4 a-h. These diones on cyclisation with N 2 H 4 yielded the title compound