Inhibitors of acyl-CoA: Cholesterol O-ac
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Patrick M. O'Brien; Drago R. Sliskovic; Adele Bernabei; Timothy Hurley; Maureen
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Article
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1995
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Elsevier Science
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English
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The syntheses and biological activities for anilides derived from 2-phenyl-2-(dodecyl-2H-tetrazol-5-yl)acetic acid are described. Evidence is provided that one of these compounds, (+)-8b, stereoselectively inhibits ACAT in vitro and possesses superior efficacy in vivo compared to (-)-8b or the racem