Cover Picture: Design, Synthesis, and Pr
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Rachel L. Weller; Scott R. Rajski
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Article
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2006
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John Wiley and Sons
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English
⚖ 49 KB
**The cover picture shows** the envisioned pathways for how the DNA methyltransferase, M.HhaI, can use either __S__‐adenosyl‐L‐methionine (SAM; left) or an unnatural aziridinium cofactor (right). The aziridinium ion is proposed to arise in situ from the appropriately functionalized 5′ N‐mustard prec