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Design, Synthesis, and Modeling of Novel Cyclic Thrombin Receptor-Derived Peptide Analogues of the Ser 42 -Phe-Leu-Leu-Arg 46 Motif Sequence with Fixed Conformations of Pharmacophoric Groups: Importance of a Phe/Arg/NH 2 Cluster for Receptor Activation and Implications in the Design of Nonpeptide Thrombin Receptor Mimetics †

✍ Scribed by Alexopoulos, Kostas; Panagiotopoulos, Dimitris; Mavromoustakos, Thomas; Fatseas, Panagiotis; Paredes-Carbajal, Maria Christina; Mascher, Dieter; Mihailescu, Stefan; Matsoukas, John

Book ID: 126825712
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 390 KB
Volume: 44
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0001525

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