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Design, synthesis and H1-antihistaminic activity of novel 1-substituted-4-(3-chlorophenyl)-[1,2,4] triazolo [4,3-a] quinazolin-5(4H)-ones

✍ Scribed by Gobinath, Manavalan; Subramanian, Natesan; Alagarsamy, Veerachamy

Book ID: 123582770
Publisher: Elsevier
Year: 2015
Tongue: English
Weight: 448 KB
Volume: 19
Category: Article
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2012.02.006

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## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin