Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β 3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder
✍ Scribed by Moyes, Christopher R.; Berger, Richard; Goble, Stephen D.; Harper, Bart; Shen, Dong-Ming; Wang, Liping; Bansal, Alka; Brown, Patricia N.; Chen, Airu S.; Dingley, Karen H.; Di Salvo, Jerry; Fitzmaurice, Aileen; Gichuru, Loise N.; Hurley, Amanda L.; Jochnowitz, Nina; Miller, Randall R.; Mistry, Shruty; Nagabukuro, Hiroshi; Salituro, Gino M.; Sanfiz, Anthony; Stevenson, Andra S.; Villa, Katherine; Zamlynny, Beata; Struthers, Mary; Weber, Ann E.; Edmondson, Scott D.
- Book ID
- 125519110
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 731 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A novel class of human b 3 -adrenergic receptor agonists was designed in effort to improve selectivity and metabolic stability versus previous disclosed b 3 -AR agonists. As observed, many of the b 3 -AR agonists seem to need the acyclic ethanolamine core for agonist activity. We have synthesized de