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Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1-yl)phenanthridine analogues as antimycobacterial agents

โœ Scribed by Nagesh, Hunsur Nagendra; Naidu, Kalaga Mahalakshmi; Rao, Damarla Harika; Sridevi, Jonnalagadda Padma; Sriram, Dharmarajan; Yogeeswari, Perumal; Chandra Sekhar, Kondapalli Venkata Gowri


Book ID
121422795
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
875 KB
Volume
23
Category
Article
ISSN
0960-894X

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## Abstract A series of 4ฮฒโ€[(4โ€substituted)โ€1,2,3โ€triazolโ€1โ€yl]podophyllotoxin analogues have been synthesized with high regioโ€selectivity by employing copper(I)โ€catalyzed 1,3โ€dipolar cycloaddition of 1โ€__O__โ€propargyl monosaccharides with C4ฮฒโ€azido podophyllotoxin and C4ฮฒโ€azidoโ€4โ€ฒโ€__O__โ€demethyl p