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Design, synthesis and characterization of captopril prodrugs for enhanced percutaneous absorption

โœ Scribed by Gary P. Moss; Darren R. Gullick; Paul A. Cox; Cameron Alexander; Matthew J. Ingram; John D. Smart; W. John Pugh

Book ID
111770490
Publisher
Pharmaceutical Press
Year
2006
Tongue
English
Weight
401 KB
Volume
58
Category
Article
ISSN
2042-7158

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## Abstract Silybin, the main component of silymarin, is an antihepatotoxic agent. But it presents numerous challenges associated with its poor aqueous solubility which has been realized as the major problem in its dosage form development and clinical application. The objective of our study was to