๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1

โœ Scribed by Daniel Spinks; Dr. Han B. Ong; Dr. Chidochangu P. Mpamhanga; Dr. Emma J. Shanks; Dr. David A. Robinson; Iain T. Collie; Dr. Kevin D. Read; Prof. Julie A. Frearson; Prof. Paul G. Wyatt; Dr. Ruth Brenk; Prof. Alan H. Fairlamb; Prof. Ian H. Gilbert


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
526 KB
Volume
6
Category
Article
ISSN
1860-7179

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Design, Synthesis and Biological Evaluat
โœ Daniel Spinks; Dr. Leah S. Torrie; Dr. Stephen Thompson; Dr. Justin R. Harrison; ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 318 KB ๐Ÿ‘ 1 views

Trypanothione synthetase (TryS) is essential for the survival of the protozoan parasite __Trypanosoma brucei__, which causes human African trypanosomiasis. It is one of only a handful of chemically validated targets for __T. brucei__ in vivo. To identify novel inhibitors of __Tb__TryS we screened ou