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Design, Synthesis, and Biological Evaluation of Novel Anti-VZV Agents

✍ Scribed by Marco Derudas; Christopher McGuigan; Robert Snoeck; Graciella Andrei; Erik De Clercq; Jan Balzarini


Book ID
113457527
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
67 KB
Volume
74
Category
Article
ISSN
0166-3542

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## Abstract Five novel compounds composed of etoposide and 5‐fluorouracil derivatives joined by an ester linkage were prepared and evaluated for their antitumor potential. Most of these analogues have exhibited promising __in vitro__ cytotoxic activity against cell cultures of murine leukaemia P‐38