𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design, Synthesis and Biological Evaluation of 4-Amino- N -(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation

✍ Scribed by Rilova, Elodie; Erdmann, Alexandre; Gros, Christina; Masson, Véronique; Aussagues, Yannick; Poughon-Cassabois, Valérie; Rajavelu, Arumugam; Jeltsch, Albert; Menon, Yoann; Novosad, Natacha; Gregoire, Jean-Marc; Vispé, Stéphane; Schambel, Philippe; Ausseil, Fréderic; Sautel, François; Arimondo, Paola B.; Cantagrel, Frédéric


Book ID
121729217
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
861 KB
Volume
9
Category
Article
ISSN
1860-7179

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Design, synthesis and biological evaluat
✍ Aleem Gangjee; Hiteshkumar D. Jain; Sherry F. Queener 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 75 KB

Nine novel nonclassical 2,4-diamino-6-methyl-5-thioarylsubstituted-7H-pyrrolo [2,3-d]pyrimidines 2-10 were synthesized as potential inhibitors of dihydrofolate reductase and as antitumor agents. The analogues contain various electron donating and electron withdrawing substituents on the phenylsulfan