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Design, Pharmacokinetic, and Pharmacodynamic Evaluation of a New Class of Soft Anticholinergics

✍ Scribed by Fenglei Huang; Clinton E. Browne; Whei-Mei Wu; Attila Juhász; Fubao Ji; Nicholas Bodor


Book ID
111557947
Publisher
Springer US
Year
2003
Tongue
English
Weight
190 KB
Volume
20
Category
Article
ISSN
0724-8741

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The design and evaluation of two new soft anticholinergic agents, ethoxycarbonylphenylcyclopentylacetyl-N,N-dimethyltropinium methyl sulfate (PCMS-1) and methoxycarbonylphenylcyclopentylacetyl-N,N-dimethyltropinium methyl sulfate (PCMS-2) are presented. According to the inactive metabolite approach